Does buying digital inventory programmatically for your advertising really work? The answer depends on who you ask. But consider the number of websites on the web. The online world is incredibly fragmented. Working with individual websites cannot provide the depth and breadth needed to achieve any kind of acceptable reach and frequency with a targeted audience. Programmatic advertising can deliver an audience on a large scale through content and behavior. Qualified online professionals provide optimization techniques to deliver an audience to your website at a very effective cost. Does Programmatic advertising work? It depends.